Anti-Human SLC1A5 Recombinant Antibody (TAB-1010CLV) (CAT#: TAB-1010CLV)

1. Q 1: What are the primary applications of the Anti-Human SLC1A5 Recombinant Antibody in research?

   A: The Anti-Human SLC1A5 Recombinant Antibody is primarily used in cancer research, particularly in understanding how SLC1A5, a neutral amino acid transporter, contributes to cancer cell metabolism and growth. It has applications in flow cytometry, antibody-dependent cellular cytotoxicity (ADCC), and complement-dependent cytotoxicity (CDC) assays, aiding in analyzing cellular responses and interactions tied to SLC1A5's functionality in tumor cells.

2. Q 2: What makes this antibody specific in targeting SLC1A5?

   A: This antibody exhibits high specificity for the human SLC1A5 transporter, ensuring accurate binding to its target. This specificity facilitates detailed studies of its expression and function in various tissue types, particularly those with elevated SLC1A5 levels, like many tumor tissues. The chimeric nature (mouse/human) ensures reduced immunogenicity in human studies.

3. Q 3: In what tissues is SLC1A5 predominantly expressed, and why is this important?

   A: SLC1A5 is predominantly expressed in tissues such as the salivary gland, colon, epididymis, and certain cancerous tissues. This expression pattern highlights its physiological and pathological roles, where it may contribute to nutrient absorption and cellular proliferation in both healthy and cancerous states, offering insights into tissue-specific function and pathology.

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